During the formation of cancer is known to take a long time, but in certain cases of cancer grows rapidly or instantaneously. Now British researchers solved the mystery of the instant cancer.
“Many cases of cancer that takes years or decades to develop. But we also know that in some cancer patients, this seems to arise more quickly than that, “said Dr Peter Campbell, as quoted from Dailymail, Friday (7 / 1).
In some cases, a single explosion in the cell can cause a lot of DNA damage. Findings from the Wellcome Trust Sanger Institute is opposed to the old theory that reveals that cancer is a consequence of hundreds or thousands of mutations that is built up.
This helps explain why some people can be diagnosed with cancer, whereas a few months earlier found no sign of disease
in X-ray ray examination or other tests. These results are based on the study of genetic damage in 750 tumors.
In most cases, damage to chromosomes in the cancer creeping up over the years. But the estimated 1 in 40 cases the tumor does not develop properly and be quick. This is based on data in a report in the journal Cell.
“These results surprised us. It seems in one cell and one incident, there are one or more chromosomes that exploded and became hundreds of fragments (fragments). Stitch this fragment will amalgamate and form a genome damage, making a rapid progression of cancer, “he said.
Dr Campbell said the broken cells is trying to reunite the pieces of chromosome fragments. But unfortunately this unification process to form the genome is shorter and can be a path to cancer. This phenomenon is very common in bone cancer, in which different damage patterns seen in 1 out of 4 cases.
Although researchers have not been too sure what triggers major damage behind this instant cancer, but possibly due to X-ray exposure and sunburn.
“If we can understand up to the root, then we can learn to deal with how to prevent these cancers,” said Dr Campbell.

Thrush or stomatitis is an inflammation that occurs in oral mucosa, usually in the form of yellowish white spots. Spots that can be single spots or groups. Thrush can affect the mucous membranes of the inner cheek, inner lip, tongue, gums, and palate in the oral cavity. Although not classified as dangerous, but very annoying canker sores.
Thrush can be caused by the condition of the mouth itself, such as poor oral hygiene, the installation of dentures, sores in the mouth because the food or drink that is too hot, and the condition of the body, such as allergies or infection.
Sprue synonymous with lack of vitamin C. Lack of vitamin is indeed cause tissue in the oral cavity and the connective tissue between the gums and teeth tear that eventually led to canker sores. However, these conditions can be overcome if we frequently eat fruits and vegetables.
Sprue is generally characterized by a burning pain that sometimes causes the patient is difficult to swallow food, and if it is severe can cause fever. Impaired thrush can affect anyone, including infants who were aged 6-24 months.
Many studies show that psychological factors (such as emotions and stress) is an important cause of canker sores. Other conditions are thought to trigger canker sores are deficient in vitamin B, vitamin C, and iron; bite wounds on the lips or tongue due to irregular tooth arrangement; injury because brushing too hard toothbrush or hair that has been developing an allergy to a food ( such chilli and pineapple), hormonal disorders (such as before or after menstruation); decreased immunity (after a prolonged illness or stress), and the presence of infection by microorganisms.
Thrush can be mitigated by using several types of drugs, either in the form of an ointment (containing antibiotics and pain relievers), drops, and mouthwash. Currently, many toothpastes available that can reduce the occurrence of canker sores. If canker sores are already severe, to use antibiotics and febrifuge (when accompanied by fever). Sprue generally will recover within 4 days. However, if canker sores do not heal, consult a doctor, because it could be early symptoms of mouth cancer.
There are many ways you can do to prevent canker sores, among others, avoid stressful conditions; frequently eat fruits and vegetables, especially those containing vitamin B, vitamin C, and iron; maintain health or oral hygiene, and avoid foods and drugs drugs that can cause allergic reactions in the oral cavity.
During this time, a common cause of thrush in the population is alcohol, soft drinks, coffee and tea, or food and other beverages in which the patient should be able to recognize themselves on the food / drinks that trigger canker sores, as if consuming food / drink is the sprue will arise . Drinking or eating foods that are too cold or too hot can cause canker sores.
It is true, vitamins are also very influential in the incidence of canker sores, but usually with the development of the era now, it’s not hard to eat nutritious food so that it can prevent the onset of canker sores from lack of vitamins.
Other causes are infection, generally occurring infection is a fungal infection resulting from the use of an old antibiotic that kills broad spectrum of its normal flora in the mouth. Where as a result, there was a disturbance of balance so that the normal flora of the oral cavity can result in the growth of other pathogenic bacteria and thrush is one of the clinical appearance. Thrush can also occur in patients after radiation or chemotherapy that cancer patients.
While systemic factors are usually found because of autoimmunity or imunocompromized (decrease in immune system) such as lupus, stomatitis apthousa, HIV, etc.. Another factor, apparently canker sores can also be caused by psychological factors a person.
So a lot of which can cause thrush, yes sir! For that, I would suggest if worried about thrush that arise continuously, you should consult and consult with a doctor you trust to make the diagnosis. Thus, treatment can be given as the cause of your canker sores. Hope this helps.

The new study found that breast cancer patients gene information could help physicians determine whether chemotherapy is effective in combating the type of cancer that annually kill millions of women in the world.
Choose between effective treatment and preventive surgery is an important decision in the fight against breast cancer. New research concludes that the information gene can confirm whether cancer patients chemotherapy the best choice that must be done.
Information gene has been widely used to help guide the treatment of breast cancer to predict and better prevention.
Sandra Cohen always be wary of getting breast cancer because her mother and grandmother died from the disease. But thanks to the gene test, she and her doctor can decide to perform preventive surgery. He said he now felt better and recommend genetic testing to others who have similar medical history.
The study looked at response and survival of women newly diagnosed with breast cancer in cancer treatment. This data is based on tumor samples taken from 310 patients treated with two chemotherapy drugs.
The researchers said the gene information of patients to be a good way to predict which tumors are really sensitive to chemotherapy and are resistant to chemotherapy.
Dr. Charis Eng a cancer researcher who did not participate in the study said, “Prediction is always a good idea, because if we can predict accurately, we can know. Think of “crystal ball” says this person will not recover if given the standard treatment for early stage breast cancer. That would make them more alert doctors and trying to overcome the cancer that grows longer faster or even give a very aggressive treatment. ”
The investigators agreed such a test could prevent patients treated with drugs in which their bodies do not respond or could become a more personal treatment.
Experts say the gene test also reduces the cost of health care and allow doctors to attack the malignant tumor without losing valuable time.
The experts in this study said that more needs to study more, but believe their findings will become an additional weapon in the fight against breast cancer.

World Health Organization or the World Health Organisation (WHO) confirmed that the electromagnetic wave such as the use of mobile phones could lead to the emergence of cancer cells (carcinogen).

The WHO statement is based on the increased risk of gliomas, or malignant brain cancer. Similarly, as reported by Cellular News, on Wednesday (06/01/2011).

Over the past week, approximately 31 scientists from 14 countries met in the event the International Agency for Research on Cancer (IARC) in France, to determine the risk of cancer due to exposure to electromagnetic waves.

The group discussed a variety of long-term health risks that may be caused by exposure to electromagnetic waves, especially cancer. It is considered necessary given the mobile users among teenagers and children are now increasing.

One study on the use of mobile phones by the year 2004 showed an increased risk of glioma by 40 percent on mobile phone users with an average usage of 30 minutes per day in the next 10 years.

Although still needs more supporting evidence, Dr. Jonathan Samet of the University of Southern California who acts as the lead group that claims these findings are strong enough to make all parties aware of the risk of cancer in cell phone usage.

The opinion was immediately diamini IARC Director Christopher Wild. “Given the risks to public health through the classification and findings, the need to conduct further research on excessive mobile phone use in the long run,” he explained.

“While waiting for information, it is very important for us to take pragmatic steps to reduce exposure to electromagnetic waves, such as hands-free device or an SMS,” lid Wild.

Leukemia is a malignancy of blood cells derived from bone marrow, characterized by the proliferation of white blood cells, with the addition of the manifestation of abnormal cells in the peripheral blood. This disease needs to get attention because leukemia is a malignancy of the largest at the children, all over the world to reach 30-40% of all malignancies of children.
Each established a new diagnosis of leukemia in a patient, will bring a lot of impact issues, including the readiness of mental / psychological, financial, maintenance of the old, the concern can not be cured, and complications of illness or treatment. These impacts not only to be faced parents / family of sufferers, but also by the medical officers / paramedical, hospital and other parties involved, so that the necessary efforts to overcome these problems.
Epidemiology.
Leukemia incidence varies from country to country, this is related to how the diagnosis and reporting. Incidence of leukemia each year about 3.5 cases of 100,000 children under 15 years old.
Acute leukemia in children reaches 97% of all leukemia in children, and consists of 2 types namely: Limfoblastik Acute Leukemia (ALL) 82% and Leukemia Mieloblastik (LMA) 18%. This is different from leukemia in adults, is ALL 15% and 85% LMA. Chronic Leukemia reach 3% of all leukemia in children.
The peak incidence of ALL at age 2-5 years and increased again after age 65 years, while LMA of all age groups, but incidence increases with age. Comparison of patients with male and female was 1.3: 15.
Etiology
The cause of leukemia is not known, but several factors associated with the onset of leukemia. These factors are ionizing radiation, chemicals, drugs, family (genetic), viral infections, immunodeficiency.
Increased incidence of leukemia in people exposed to radiation as happened in Hiroshima and Nagasaki after the atomic bomb. While medicine is a group alkylation (sitostatica), chloramphenicol, phenylbutazone, heksaklorosiklokeksan. According to Leiss and Savitz (1995), the use of pesticides in the home associated with the incidence of malignancy in children.
Family factors (genetic) associated with the occurrence of leukemia because of the identical twins where one twin suffering from leukemia, the risk of suffering from leukemia is also within 5 years, and the incidence of leukemia in siblings increased 4 times when one brother suffering from leukemia. Leukemia more common in children who suffer from chromosomal abnormalities like Down Sandroma, and other genetic diseases. Experiments on animals showed that the viral infection ribonucleic acid (RNA) to contribute to the emergence of leukemia, but in humans still needs further investigation.
Some conditions perinatal risk factors of leukemia in children, as reported by Cnattingis et al (1995). These factors are renal disease in the mother, the use of oxygen supplementation, post partum asphyxia, birth weight> 4500 grams, and hypertension during pregnancy. While Shu DAA (1996) reported that pregnant women who consume alcohol increase the risk of leukemia in infants, especially the LMA.
Pathogenesis
Acute leukemia is a disease with malignant transformation and expansion of clones hematopoietic cells are inhibited at the level of differentiation and can not develop into a more mature form. Blood cells derived from pluripotent stem cells hematopoesis which then differentiate into lymphoid stem and stem mieloid (non-lymphoid) multipotent. Lymphoid stem cells will form the T cells and B cells, stem cells will differentiate into cells mieloid erythrocytes, granulocytes, monocytes and megakariosit. At each stage of differentiation can occur leukemic changes into a clone of unknown cause. When this happens maturation may be disrupted, so the young will increase the number of cells and suppress the formation of normal blood cells in bone marrow. Tues leukemic can enter the blood circulation which then infiltrate the organs of the body thereby causing disruption of cell metabolism and organ function. Death in patients with acute leukemia is generally caused by rapid bone marrow suppression, and great, but can also be caused by leukemic cell infiltration into the patient’s body organs.
COMPLAINTS AND SYMPTOMS Leukemia
Gum hypertrophy mainly occurs in LMA. Infiltration into the skin, which can occur in standard and high-risk groups, often occur in the scalp, and can be an early symptom of leukemia. In boys, testicular infiltration to cause enlargement of the testicles that are not pain in one or both testicles, this will affect the prognosis for causing a relapse. Generally the symptoms in children who suffer from LMA was the result of bone marrow disorders, such as in ALL, and infiltration of organs. Swelling in the orbital soft tissues and gums are more prominent.
DIAGNOSIS
Clinical symptoms and complete blood tests to diagnose leukemia. However, to be sure to do the examination of bone marrow aspiration, and furnished with chest radiographic examination, cerebrospinal fluid, and some other investigation. This method can diagnose about 90% of cases, while the rest require further examination, namely sitokimia, immunology, cytogenetics and molecular biology.
At the time of diagnosis of leukemia is established will cause a few problems, both because of the actions invasive or psychological condition of parents and family. Bone marrow aspiration and lumbar puncture can cause pain and fear in children as well as concerns in the elderly, so we need an explanation with education, sedation and psychological approaches. Such actions are also needed when evaluating the development of disease / treatment progress, according to a predetermined schedule of education and mentoring of parents at the time of the action of bone marrow aspiration and lumbar puncture is a step that aims to reduce pain and improve patient confidence.
THERAPY
Treatment of leukemia include curative and supportive. Treatment includes supportive treatment of other diseases that accompany leukemia, complications and action to promote healing, including psychological treatment. Supportive treatments include transfusions of blood / platelets, giving antibiotics to the infection / sepsis, anti-fungal drug, providing good nutrition and psychosocial aspects of the approach.
Curative therapy / specific aims to cure patients. The general strategy of acute leukemia included induction chemotherapy remission, intensification (CNS prophylaxis) and continued. Classification of standard risk and high risk, determine the protocol chemotherapy. In the remission induction chemotherapy is given the maximum that can be tolerated and the maximum supportive care. Possible results achieved complete remission, partial remission or failed. Intensification is an additional intensive chemotherapy after complete remission and for prophylaxis occurred leukemia in the central nerve channel. The expected result is an extension of the achievement of remission and improve healing. Treatment continued until about 2 years, is expected to achieve an extension of remission and may survive.
Sitostatica used at each stage of leukemia treatment is a combination of various sitostatica. Treatment with granulocyte-colony stimulating factor (G-CSF) is useful to overcome the decline sitistatika granulocytes as side effects, but does not reduce the length of hospital care.
Patients expressed complete remission if no complaints and are free of symptoms of leukemia, the bone marrow aspirate obtained cellular normal and the number of blast cells <5% of the core cell, hemoglobin> 12 g / dL without transfusion, leukocyte cell count> 3000/μl, with the count types of normal leukocytes, the number of granulocytes> 2000 / mL, platelet count> 100,000 / mL, and normal serebropinal fluid examination.
The problem faced in handling patients with leukemia is an expensive drug, the availability of drugs that do not necessarily complete, and the presence of side effects, and care of the old. Drug for leukemia considered expensive for most patients especially the days of the current crisis, addition to the many kinds of drugs, also increase the duration of treatment costs for drug procurement. Side effects sitostatica diverse as anemia, pedarahan, hair loss, granulositopenia (ease of infection), nausea / vomiting, stomatitis, myocarditis, and so forth. Patients with granulositopenia should be treated in isolation rooms. To overcome the boredom for a long treatment is necessary to provide space to play and psychological services. Patients who had complete remission and treatment of conditions such as healthy child will recover. Problem during treatment is the occurrence relap (relapse). Relapse is a bad omen for the disease. Basically there are 3 step relapse:
Intramedular (bone marrow)
Ekstramedular (composition of the central nervous system, testis, iris)
Intra-and extra-medullary.
Relapses can occur in early relapse (early relapse) that occur during treatment or within 6 months of treatment and late relapse (late relapse), which occurred more than 6 months after treatment.
Prognosis
ALL normal risk prognosis is better than high risk. Unfavorable prognostic factors include: age less than 2 years, more than 10 years of age, the number of leukocytes (white blood cells) at the beginning of more than 50×109 / L, platelet count (platelets) less than 100×109 / L, there is the mediastinum , black race, male, no enlargement of lymph nodes, liver enlargement of more than 3 cm, L2 or L3 limfoblas type, and the presence of CNS disease at diagnosis. Viana et al (1994) found, patients with malnutrition (according to standard height / age) the risk of recurrence is higher than the nutritional well. In Singapore, although there is no improvement, 30% -40% of patients experienced a relapse, and this group good prognosis. The development and success of preventive treatment for leukemia die followed by systemic chemotherapy progressively improve ALL cure rates in children. 5-year survival rate around 66-67% ALL. In the LMA, a high leukocyte count (> 100.000/μL), black race, abnormal coagulation prognosis ugly.